题目：Modeling gene regulatory network with chromatin activity

摘要：Gene regulatory networks study the mechanism that how the gene expression is regulated and have an important role in every process of life, including cell differentiation, metabolism, cell cycle and signal transduction. Many studies indicate that genome-wide tran1111ional levels are highly correlated with chromatin state. Because cell packs a lot of genetic and regulatory information through a structure known as chromatin, i.e., DNA is wrapped around histone proteins and is tightly packed in a remarkable way. To express a gene in a specific coding region, the chromatin would open up and DNA loop may be formed by interacting enhancers and promoters.  In this talk, we will introduce our recent efforts to consider chromatin state in modeling regulatory system.

报告人：王勇研究员，中国科学院(CAS) 数学与系统科学研究院(AMSS) 应用数学所。

时间：2016年11月23日11:00-11:50

地点：中国人民大学数学科学研究院（环境楼）316会议室